Data analysis

# Analysis of MEA, Ca2+ Transient, imaging, and EEG/ECoG data, as well as correlation analysis with multiple assays and in vivo studies.

Based on a comprehensive track record of analyses aligned with evaluation models and assays, we predict the efficacy, toxicity, and mechanisms of action of compounds. We also perform analyses of data acquired by clients.

MEA Data Analysis

  • Original analysis parameters (e.g. synaptic strength) analysis

  • Multivariate analysis (including IP)

  • AI (waveforms, raster plots, parameters, etc.)

  • Frequency analysis

  • Impedance analysis

  • Network Burst Detection using 4 step method

  • Sensory neuron/DRG neuron analysis

  • Brain Organoid Analysis

  • Astrocyte Analysis

  • LTP/LTD Analysis of Brain Slice

  • FPD/Contractility analysis of cardiomyocytes

  • Visualization by heat map, radar chart notation, etc.

MEA
Data analysis
AI
HD-MEA Data Analysis

  • 1-Cell Firing Pattern Analysis

  • Intercellular Coupling Strength Analysis

  • Frequency Analysis

  • Myocardial Propagation Pattern Analysis

  • Axonal Conduction Analysis

  • Brain area propagation analysis (Slice)

  • AI (waveform, raster plot, parameters, etc.)

  • Myocardial conduction velocity analysis

HD-MEA
Image analysis (phase contrast/fluorescence images)

  • Parametric Analysis of Cellular Morphology

  • AI Analysis

  • Multivariate analysis

Ca2+Transient Analysis

  • Oscillation Algorithm

  • Multivariate Analysis

  • AI Analysis

Multiple assay/in vivo correlation analysis

  • We conduct correlation analyses of parameters obtained from multiple assays, as well as correlation analyses between in vitro and in vivo data, to improve prediction accuracy and consider the extrapolation to in vivo.

EEG analysis

  • Using our unique method of EEG/ECoG data analysis, we detect early indicators of compound toxicity.

Intellectual Property

  • Method, Computer System and Program for Predicting Properties of a Target, Patent No. 6558786, PCT Filed

  • Method, computer system and program for predicting properties of a target compound, Patent No. 6567153, PCT Pending

  • Method, computer system and program for performing burst analysis on waveform data acquired from the brain, as well as method, computer system and program for predicting the state of a target using burst analysis, Patent No. 7138995

  • Method, computer system, and program for creating a histogram image, as well as method, computer system, and program for predicting a state of a target using a histogram image, Patent No. 7099777