Data analysis

# ビックデータから、薬効、毒性、作用機序予測を行います。



Y. Ishibashi, N Nagafuku, K Kinoshita, A Okamura, T shirakawa, I Suzuki*,  Verification in seizure liability of compounds based on comparison between in vitro functional activity in cultured neurons and in vivo cerebrospinal fluid concentration for approaching in vitro to in vivo extrapolation, Toxicology and Applied pharmacology. 476;116675, 2023  DOI

Y. Ishibashi, N. Nagafuku, Y. Kanda, I. Suzuki1 * Evaluation of neurotoxicity for pesticide-related compounds in human iPS cell-derived neurons 2 using microelectrode array. Toxicology in vitro. 93;105668, 2023  DOI

Y Ishibashi, A Odawara, K Kinoshita, A Okamura, T Shirakawa, I Suzuki*. Principal Component Analysis to Distinguish Seizure Liability of Drugs in Human iPS Cell-Derived Neurons. Toxicological Sciences. 2021 184(2):265–275 DOI

R Roberts, S Authier, D Mellon, M Morton, I Suzuki, RB Tjalkens, JP Valentin, JB Pierson. Can We Panelize Seizure?. Toxicological Sciences. 2021, 179(1), 3-13 DOI


  • 標的の特性の予測を行うための方法、コンピュータシステム、プログラム, 特許第6558786号, PCT出願済